Alexander J. Fitt

This study identifies conserved molecular responses to arsenite exposure in Drosophila, revealing shared pathways with human arsenic-related diseases.

This study shows Klotho deficiency causes skeletal muscle weakness and impaired motor unit connectivity by altering neuromuscular junction structure and function.

The paper generates two novel D2hgdh loss-of-function mutations in Drosophila to study D-2HG accumulation and its effects on development and metabolism.

This study shows that L2hgdh in Drosophila renal tubules prevents L-2HG accumulation, supports mitochondrial metabolism, and enables hypoxia tolerance.

The paper investigates L-2-hydroxyglutarate (L-2HG) accumulation in 18 insect species, finding high levels in Dipterans and suggesting a potential role in their development and pest control.