Juan Ji An

A PVH-to-parabrachial BDNF circuit mediates non-aversive feeding suppression

The paper identifies a non-aversive feeding suppression circuit involving PVH-to-PBN BDNF neurons and shows their role in feeding regulation without inducing taste aversion.

Sexual dimorphism of autism-like phenotypes in microglial eIF4E overexpression mice

This study shows that sex hormones, not sex chromosomes, drive male-biased ASD-like phenotypes in microglial eIF4E overexpression mice.

Genetic dissection of BDNF and TrkB expression in glial cells

The paper uses genetic methods to investigate BDNF and TrkB expression in glial cells, finding no BDNF or TrkB in microglia and limited expression in astrocytes and oligodendrocytes.

Neurotrophin-3 from the dentate gyrus supports postsynaptic sites of mossy fiber-CA3 synapses and contextual memory

This study shows that NT3 from the dentate gyrus is essential for postsynaptic structure and function of MF-CA3 synapses and hippocampal-dependent memory.

Discrete TrkB-expressing neurons of the dorsomedial hypothalamus regulate feeding and thermogenesis

This study identifies distinct roles of TrkB-expressing neurons in the dorsomedial hypothalamus for regulating thermogenesis and feeding through specific neural projections.

TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits

This study identifies TrkB-expressing paraventricular hypothalamic neurons as key regulators of appetite through multiple neurocircuits, showing their role in suppressing food intake.