Baoji Xu

This study shows that reducing TrkB.T in astrocytes reduces amyloid plaques and prevents synaptic loss in 5xFAD mice by enhancing BDNF-TrkB.FL signaling.

The paper identifies a non-aversive feeding suppression circuit involving PVH-to-PBN BDNF neurons and shows their role in feeding regulation without inducing taste aversion.

This study shows that sex hormones, not sex chromosomes, drive male-biased ASD-like phenotypes in microglial eIF4E overexpression mice.

This study identifies a molecular clock in the prelimbic cortex that regulates protein synthesis for memory consolidation and reconsolidation through distinct translational pathways.

This study shows that loss of FMRP in microglia reduces PV neuron density and causes audiogenic seizures by impairing lysosomal function and progranulin levels.

The paper uses genetic methods to investigate BDNF and TrkB expression in glial cells, finding no BDNF or TrkB in microglia and limited expression in astrocytes and oligodendrocytes.

This study shows that NT3 from the dentate gyrus is essential for postsynaptic structure and function of MF-CA3 synapses and hippocampal-dependent memory.

This study identifies distinct roles of TrkB-expressing neurons in the dorsomedial hypothalamus for regulating thermogenesis and feeding through specific neural projections.

This study identifies TrkB-expressing paraventricular hypothalamic neurons as key regulators of appetite through multiple neurocircuits, showing their role in suppressing food intake.