Genome-wide multi-trait analysis of irritable bowel syndrome and related mental conditions identifies 38 new genetic hits
Silvia Alemany, María Soler Artigas, Judit Cabana‐Domínguez, Dana Fakhreddine, Natalia Llonga, Laura Vilar‐Ribó, Amanda Rodríguez‐Urrutia, Judit Palacio, Ana María González-Castro, Beatriz Lobo, Carmen Alonso, Magnus Simrén, Javier Santos, Josep Antoni Ramos‐Quiroga, Marta Ribasés
This study identifies 38 new genetic loci for irritable bowel syndrome through a multi-trait genome-wide association analysis, revealing genetic overlaps with mental conditions and potential causal relationships.
medRxiv · Jan 30, 2023 · PreprintGenetic & Genomic Medicine