Spatiotemporal atlas resolves the mesenchymal-epithelial stem cell axis governing human hair follicle aging and pathology
Xiaoyu Wei, Yanwen Xu, Jiaxin Du, Ruikang Li, Zhentao Zhou, Yeya Yu, Zishuo Yuan, Hanxiao Cheng, Yujia Jiang, Fei Zhu, Pengfei Cai, Haiyan Shen, Shuai Wang, Yue Yuan, Xiawei Liu, , Jufang Zhang
This study creates a spatiotemporal atlas to understand mesenchymal-epithelial stem cell dynamics in human hair follicle aging and androgenetic alopecia, identifying PTN as a key regenerative factor.
bioRxiv · Sep 23, 2026 · PreprintCell Biology