Hanbo Li

This study creates a spatiotemporal atlas to understand mesenchymal-epithelial stem cell dynamics in human hair follicle aging and androgenetic alopecia, identifying PTN as a key regenerative factor.

This study reconstructs 3D spatial transcriptomic models of planarians to map cell type distribution and positional gene regulation, identifying candidate genes involved in regeneration.

This study constructs a 4D spatiotemporal transcriptomic map of planarian regeneration using Stereo-seq, identifying dynamic gradients and an injury-induced regenerative zone.

The paper develops ACCESS, a multimodal graph neural network to annotate functional dark matter proteins from extreme environments beyond homology-based methods.

This study identifies divergent stem cell mechanisms in axolotl tail and limb regeneration, showing that TGF-β signaling determines lineage fate of muscle stem cells.

This study identifies and characterizes over one million urinary cell free eccDNAs in healthy adults, revealing their genomic distribution, sequence features, and potential role of direct repeats in their biogenesis.

The paper analyzes 630 aquatic vertebrate genomes to create a compendium, revealing TE diversity and gene family evolution related to the water-to-land transition.

The paper uses Stereo-seq to map single-cell transcriptomes of axolotl telencephalon during development and regeneration, identifying a key radial glial cell subtype involved in early wound healing.

The paper reports the chromosome-level genome of the white-spotted bamboo shark and shows chromosome rearrangements contribute to phenotypic diversity in cartilaginous fishes.