Detection of functional protein domains by unbiased genome-wide forward genetic screening
Mareike Herzog, Fabio Puddu, Julia Coates, Nicola J. Geisler, Josep V. Forment, Stephen P. Jackson
This paper describes a method to detect functional protein domains by identifying suppressor mutations in yeast and mouse cells, revealing insights into protein function and drug resistance mechanisms.
Scientific Reports · Apr 12, 2018Peer-reviewedMolecular Biology