Hyaluronan underlies the emergence of form, fate, and function in human cardioids
Stefan M. Jahnel, Anna Dimitriadi, Julia Kodnar, Vasileios Gerakopoulos, Yajushi Khurana, Maximilian Mayrhauser, Tobias Ilmer, Mohamed Amin Elaguech, Adam R. Hall, Keisuke Ishihara, Sasha Mendjan
This study shows hyaluronan drives cavity formation, cell identity, and function in human cardioids through mechanical and bioscaffolding roles.
bioRxiv · May 20, 2026 · PreprintDevelopmental Biology