Stefan M. Jahnel

This study shows hyaluronan drives cavity formation, cell identity, and function in human cardioids through mechanical and bioscaffolding roles.

This paper develops a multi-chamber cardioid platform to study human heart development and defects by generating compartment-specific gene expression, morphology, and function.

The study identifies gene duplications and co-option of effector modules as mechanisms driving muscle cell type diversification in sea anemones.

This paper establishes self-organizing cardioids from human pluripotent stem cells that form chamber-like structures and identifies signaling pathways governing their development.