Progression of the cardiac phenotype of the DE50-MD dog model of Duchenne Muscular Dystrophy, corroborating results of cardiac magnetic resonance imaging with pathology up to 36 months of age.
Julia Sargent, Virginia Luis Fuentes, Rebecca L. Terry, Dominique O. Riddell, Rachel C. M. Harron, Dominic J. Wells, Richard J. Piercy
This study tracks cardiac changes in DE50-MD dogs with DMD, showing worsening fibrosis and function decline over time, validated by CMR and histopathology.
bioRxiv · Feb 28, 2025 · PreprintPathology