Interface integrity in septin protofilaments is maintained by an arginine residue conserved from yeast to man.
Benjamin Grupp, Jano Benito Graser, Julia Seifermann, S. Gerhardt, Justin A. Lemkul, Jan Felix Gehrke, Nils Johnsson, Thomas Gronemeyer
The paper identifies a conserved arginine residue critical for maintaining interface integrity in septin protofilaments across species using molecular dynamics simulations and experimental validation.
Molecular Biology of the Cell · Mar 26, 2025Peer-reviewedBiochemistry