S. Gerhardt

This study identifies a nucleotide-triggered mechanism that stabilizes the G-interface and enables NC-interface assembly in septins, revealing unidirectional allosteric signaling during filament formation.

The paper identifies a conserved arginine residue critical for maintaining interface integrity in septin protofilaments across species using molecular dynamics simulations and experimental validation.

This study characterizes two PPK2 enzymes, showing their broad substrate specificity and ability to selectively synthesize pyrimidine nucleoside diphosphates with high yield.