Author

Jan Felix Gehrke

Universität UlmORCID 0009-0003-4839-0650Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Organism:yeast· 1

Frequent Co-Authors

Benjamin GruppiD· 2 shared Nils JohnssoniD· 2 shared S. GerhardtiD· 2 shared Thomas GronemeyeriD· 2 shared Assmann GunteriD· 1 shared Benjamin JäckeliD· 1 shared Christian Sieg· 1 shared Erik SchleicheriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Benjamin GruppORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMay 11, 2026

A nucleotide-triggered molecular switch orchestrating septin polymerization

Benjamin Grupp, Benjamin Jäckel, Assmann Gunter…·Thomas Gronemeyer

This study identifies a nucleotide-triggered mechanism that stabilizes the G-interface and enables NC-interface assembly in septins, revealing unidirectional allosteric signaling during filament formation.

DOI 10.64898/2026.05.07.723466

experimental assay

𝕏 PostBluesky

BiochemistryMolecular Biology of the CellPeer-reviewedMar 26, 2025

Interface integrity in septin protofilaments is maintained by an arginine residue conserved from yeast to man.

Benjamin Grupp, Jano Benito Graser, Julia Seifermann…·Thomas Gronemeyer

The paper identifies a conserved arginine residue critical for maintaining interface integrity in septin protofilaments across species using molecular dynamics simulations and experimental validation.

3 citations

humanyeast

𝕏 PostBluesky