Author

Julianne Rieders

Children's Hospital of Philadelphia

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Adina Singer· 1 shared Alice S. Chen‐PlotkiniD· 1 shared Beverly L. DavidsoniD· 1 shared Defne A. AmadoiD· 1 shared Eric LancasteriD· 1 shared Fortunay H. DiattaiD· 1 shared Jordan T. MakiD· 1 shared Junxian ZhangiD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperNeuroscience

Adina Singer

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1 paper

Recent·Most cited

AAV-mediated progranulin delivery to a mouse model of progranulin deficiency causes T cell-mediated hippocampal degeneration

Defne A. Amado, Julianne Rieders, Fortunay H. Diatta, Pilar Hernandez‐Con, Adina Singer, Jordan T. Mak, Junxian Zhang, Eric Lancaster, Beverly L. Davidson, Alice S. Chen‐Plotkin

This study shows that AAV-mediated GRN overexpression in mice causes hippocampal degeneration and T cell infiltration, raising safety concerns for GRN-based CNS gene therapies.

Molecular Therapy · Nov 16, 2018Peer-reviewedNeuroscience