Author

Pilar Hernandez‐Con

University of PennsylvaniaORCID 0000-0003-4959-9141Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Adina Singer· 1 shared Alice S. Chen‐PlotkiniD· 1 shared Beverly L. DavidsoniD· 1 shared Defne A. AmadoiD· 1 shared Eric LancasteriD· 1 shared Fortunay H. DiattaiD· 1 shared Jordan T. MakiD· 1 shared Julianne Rieders· 1 shared

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2018-2018 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperNeuroscience

Adina Singer

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1 paper

Recent·Most cited

NeuroscienceMolecular TherapyPeer-reviewedNov 16, 2018

AAV-mediated progranulin delivery to a mouse model of progranulin deficiency causes T cell-mediated hippocampal degeneration

Defne A. Amado, Julianne Rieders, Fortunay H. Diatta…·Alice S. Chen‐Plotkin

This study shows that AAV-mediated GRN overexpression in mice causes hippocampal degeneration and T cell infiltration, raising safety concerns for GRN-based CNS gene therapies.

58 citationstop 4%

mouseexperimental assay

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