The R2TP chaperone assembles cellular machineries in intestinal CBC stem cells and progenitors
Chloé Maurizy, Claire Abéza, Bénédicte Lemmers, Monica Gabola, Ciro Longobardi, Valérie Pinet, Marina Ferrand, Conception Paul, Julie Bremond, Francina Langa Vives, François Gerbe, Philippe Jay, Céline Verheggen, Nicola Tinari, Dominique Helmlinger, , Bérengère Pradet‐Balade
This study investigates the role of the R2TP chaperone in intestinal stem and progenitor cells, showing its critical function in proliferation and its association with poor colorectal cancer prognosis.
Nature Communications · Aug 10, 2021Peer-reviewedDevelopmental Biology