The MET growth signaling complex drives Alzheimers Disease-associated brain pathology in aged Shugoshin 1 mouse cohesinopathy model
Chinthalapally V. Rao, Julie Crane, Ben Fowler, Yuting Zhang, Hiroshi Y. Yamada
This study identifies oncogenic MET signaling activation in aged Sgo1-/+ mice brains, linking it to Alzheimer's Disease pathology and suggesting potential drug repurposing.
bioRxiv · Mar 26, 2024 · PreprintNeuroscience