Author

Chinthalapally V. Rao

Oklahoma Medical Research FoundationORCID 0000-0002-5715-7979Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

Albert Tran· 1 shared Ben Fowler· 1 shared Bo Hagy· 1 shared Chao JiangiD· 1 shared Constantin GeorgescuiD· 1 shared Courtney W. HoucheniD· 1 shared Hiroshi Y. YamadaiD· 1 shared Jonathan D. WreniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Albert Tran

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2 papers

Recent·Most cited

Hepatocyte MLKL Drives Obesity-Driven Hepatocellular Carcinoma Progression via Mitochondrial Dysfunction Independent of Necroptosis in MASLD

Phoebe Ohene-Marfo, Sabira Mohammed, Chao Jiang, Shylesh Bhaskaran, Kara Kneuper, Satoshi Matsuzaki, Bo Hagy, Randal J. May, Constantin Georgescu, Megan John, Julianne N. Hoang, Kevin Pham, Albert Tran, Chinthalapally V. Rao, Tae Gyu Oh, , Sathyaseelan S. Deepa

This study shows that hepatocyte MLKL promotes obesity-driven MASLD-HCC through mitochondrial dysfunction and MFN2 suppression, independent of necroptosis.

Hepatology · Aug 4, 2026Peer-reviewedCancer Biology

The MET growth signaling complex drives Alzheimers Disease-associated brain pathology in aged Shugoshin 1 mouse cohesinopathy model

Chinthalapally V. Rao, Julie Crane, Ben Fowler, Yuting Zhang, Hiroshi Y. Yamada

This study identifies oncogenic MET signaling activation in aged Sgo1-/+ mice brains, linking it to Alzheimer's Disease pathology and suggesting potential drug repurposing.

bioRxiv · Mar 26, 2024 · PreprintNeuroscience