The Smac mimetic drug Xevinapant sensitizes triple negative breast cancer to radiotherapy-induced cell death in a TNFα dependent manner
Mame Daro Faye, Julie Lafontaine, Philip Wong, Cynthia M. Ménard
This study shows Xevinapant enhances radiotherapy-induced cell death in TNBC cells, with TNFα playing a key role in this effect.
bioRxiv · Oct 1, 2026 · PreprintCancer Biology