A 3-dimensional molecular cartography of human cerebral organoids revealed by double-barcoded spatial transcriptomics
Gwendoline Lozachmeur, Aude Bramoulle, Antoine Aubert, François Stüder, Julien Moehlin, Lucie Madrange, Frank Yates, Jean‐Philippe Deslys, Marco Antonio Mendoza-Parra
This study develops a low-cost method for spatial transcriptomics and applies it to create a 3D molecular map of human brain organoids, showing gene expression differences across sections.
bioRxiv · Jan 18, 2023 · PreprintSystems Biology