Anxiety-like but not despair-like behaviors are further aggravated by chronic mild stress in the early stages of APPswe/PS1dE9 transgenic mice
Jun-Ying Gao, Ying Chen, Dong-Yuan Su, Charles Marshall, Ming Xiao
This study shows chronic mild stress worsens anxiety-like behaviors but not despair-like behaviors in early AD mouse models, along with increased neuroinflammation and corticosterone normalization.
bioRxiv · Oct 12, 2017 · PreprintAnimal Behavior & Cognition