Large-scale integration of omics and electronic health records to identify potential risk protein biomarkers and therapeutic drugs for cancer prevention
Qing Li, Qingyuan Song, Zhishan Chen, Jung-Yoon Choi, Victor Rau Moreno, Jie Ping, Wanqing Wen, Chao Li, Xiang Shu, Jun Yan, Xiao‐Ou Shu, Qiuyin Cai, Jirong Long, Jeroen R. Huyghe, Rish K. Pai, , Xingyi Guo
This study integrates large-scale omics and electronic health records to identify risk proteins and drugs for cancer prevention, finding 101 novel proteins and three drugs associated with reduced colorectal cancer risk.
The American Journal of Human Genetics · Dec 2, 2025Peer-reviewedGenetic & Genomic Medicine