Cell competition confers anchorage plasticity of disseminated tumor cells
Hyunbin D. Huh, Yujin Sub, Jee Hung Kim, Hannah Lee, Jongwook Oh, Dong Ki Lee, Jong Hwa Byun, Woo Yang Pyun, Sehyung Pak, Junjeong Choi, Tadayoshi Hashimoto, Takayuki Yoshino, Joon Jeong, Heon Yung Gee, Hyun Woo Park
The paper shows cell competition enables loser cells to gain metastatic potential through anchorage plasticity, mediated by AST factors, and demonstrates this in breast cancer metastasis.
bioRxiv · Nov 25, 2024 · PreprintCancer Biology