Yujin Sub

Adherent-to-suspension transition promotes melanoma metastatic dissemination

This study shows that the adherent-to-suspension transition in melanoma cells enhances metastatic potential by reprogramming anchorage dependency, independent of epithelial-to-mesenchymal-like transition pathways.

Cell competition confers anchorage plasticity of disseminated tumor cells

The paper shows cell competition enables loser cells to gain metastatic potential through anchorage plasticity, mediated by AST factors, and demonstrates this in breast cancer metastasis.