Epitranscriptomic Modification of MicroRNA Increases Atherosclerosis Susceptibility
Ming He, Jianjie Dong, Junmao Wen, Yuqing Zhang, So Yun Han, Chen Wang, Brendan Gongol, Tong‐You Wade Wei, Jian Kang, Hsi‐Yuan Huang, Susan C. Cheng, John Y.-J. Shyy
This study shows that oxidative stress modifies miR-483 to 8OH-G miR-483, leading to endothelial dysfunction and increased atherosclerosis risk through altered targetomes.
Circulation · Nov 27, 2023Peer-reviewedMolecular Biology