HSP90α is specifically required for rod photoreceptor function and cannot be replaced by HSP90β.
Juri Hoda, Hunter Lee Aliff, Wentao Deng, Visvanathan Ramamurthy
The paper shows HSP90 is essential for rod photoreceptor function and cannot be replaced by HSP90β, using AAV-mediated gene delivery in Hsp90 knockout mice.
bioRxiv · Jun 5, 2025 · PreprintBiochemistry