Wentao Deng

This study shows that CCN4 promotes immunosuppression in breast cancer by altering the tumor microenvironment and immune cell composition.

The paper identifies a mature dendritic cell subtype associated with improved immune response and prognosis in melanoma patients treated with anti-PD-1 checkpoint inhibitors.

This study compares the functional characteristics of two melanoma models, B16F0 and YUMM1.7, finding differences in tumor growth, chemosensitivity, and immunogenicity that suggest different applications for each model.

The paper shows HSP90 is essential for rod photoreceptor function and cannot be replaced by HSP90β, using AAV-mediated gene delivery in Hsp90 knockout mice.

The paper uses Bayesian network inference and digital cytometry to model how oncogenic gene expression alters tumor microenvironments from bulk transcriptomic data.