BiochemistrybioRxivPreprint
Structural and Dynamical Analyses of Apo and Cap-binding eIF4E: An in silico Study
Karin Hasegawa, Justin Burzachiello, Liam Connolly…·Yuefan Deng
This study uses molecular dynamics simulations to analyze structural changes in eIF4E when bound to Cap and in its apo form, identifying key residues involved in conformational transitions and suggesting targets for drug design.
DOI 10.1101/2024.05.18.594816