NLRP1B allele 2 does not respond to Val-boro-Pro (VbP) in the intestinal epithelium
Ryan J. Mazzone, Nathaniel J. Winsor, Lu Yi Li, Kristian T. Barry, Adrienne Ranger, Shawn Goyal, Justin J. Meade, Jessica K. Bruce, Dana J. Philpott, Jeremy Mogridge, Stephen E. Girardin
This study shows that NLRP1B allele 2 in intestinal epithelial cells does not respond to VbP, unlike in macrophages, suggesting allele-dependent regulation in IECs.
bioRxiv · Jul 18, 2024 · PreprintImmunology