Author

Stephen E. Girardin

University of TorontoORCID 0000-0001-9208-8879Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Dana J. PhilpottiD· 2 shared Adrienne RangeriD· 1 shared Alexander Luchak· 1 shared Bana SammaniD· 1 shared Boyan K. TsankoviD· 1 shared Charles CarriD· 1 shared Derek K.L. TsangiD· 1 shared Elaine Tam· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Dana J. PhilpottORCID

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2 papers

Recent·Most cited

ImmunologyNature ImmunologyPeer-reviewedJul 20, 2026

Endothelial cell-intrinsic NOD2 signaling regulates the intestinal immune response through the generation of effector and memory T cells.

Boyan K. Tsankov, Madison Denney, Jennifer S. Y. Ahn…·Dana J. Philpott

This study shows that NOD2 signaling in endothelial cells regulates intestinal immune responses by promoting T cell homing and memory formation, and its loss contributes to Crohn's disease inflammation.

1 citation

mouseproteomics

𝕏 PostBluesky

ImmunologybioRxivPreprintJul 18, 2024

NLRP1B allele 2 does not respond to Val-boro-Pro (VbP) in the intestinal epithelium

Ryan J. Mazzone, Nathaniel J. Winsor, Lu Yi Li…·Stephen E. Girardin

This study shows that NLRP1B allele 2 in intestinal epithelial cells does not respond to VbP, unlike in macrophages, suggesting allele-dependent regulation in IECs.

DOI 10.1101/2024.07.18.604161

mouseproteomics

𝕏 PostBluesky