Therapeutic scheduling of WEE1 inhibition preserves T cell function and promotes immune control of HPV+ tumors
Ying Liu, Zhiheng Zhang, Yanshan Tao, Lovely Rahgav, Sophie L. Gray-Gaillard, Yasser Hussaini, Meijie Pan, Justine Shamber, Jeff Kwak, Simone L. Park, Jessica Cramer, Regina Stoltz, Joseph N. Patria, Jherek Swanger, Kathryn Liu, , Ahmed Diab
This study shows that intermittent WEE1 inhibition preserves T cell function and enhances immune control of HPV+ tumors through non-cell-autonomous immune activation mechanisms.
bioRxiv · Mar 17, 2026 · PreprintCancer Biology