Caprin-1 binding to the critical stress granule protein G3BP1 is regulated by pH
T. Schulte, M. D. Panas, L. Wiliams, N. Kedersha, J. S. Fleck, T. J. C. Tan, A. Olsson, A. M. Morro, L. Hanke, J. Nilvebrant, K. A. Giang, P.-A. Nygren, P. Anderson, A. Achour, G. M. McInerney
This study shows that Caprin-1 binds to G3BP1's NTF2 domain with pH sensitivity, regulating stress granule formation through a SLiM-mediated mechanism.
bioRxiv · Feb 5, 2021Biochemistry