Author

J. S. Fleck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Research Focus:protein folding & dynamics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. Achour· 1 shared A. M. Morro· 1 shared A. Olsson· 1 shared B. Treutlein· 1 shared D. Klein· 1 shared F. J. Theis· 1 shared G. M. McInerney· 1 shared G. Maciag· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Achour

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

An integrated transcriptomic cell atlas of human endoderm-derived organoids

Q. Xu, L. Halle, S. Hediyeh-zadeh, M. Kuijs, U. Kilik, Q. Yu, T. Frum, L. Adam, S. Parikh, M. Gander, R. Kfuri-Rubens, D. Klein, Z. He, J. S. Fleck, K. Oost, , J. G. Camp

This paper creates a human endoderm organoid cell atlas by integrating single-cell transcriptomes from multiple organoid types to compare cell states with primary tissues and disease models.

bioRxiv · Nov 20, 2023Cell Biology

Caprin-1 binding to the critical stress granule protein G3BP1 is regulated by pH

T. Schulte, M. D. Panas, L. Wiliams, N. Kedersha, J. S. Fleck, T. J. C. Tan, A. Olsson, A. M. Morro, L. Hanke, J. Nilvebrant, K. A. Giang, P.-A. Nygren, P. Anderson, A. Achour, G. M. McInerney

This study shows that Caprin-1 binds to G3BP1's NTF2 domain with pH sensitivity, regulating stress granule formation through a SLiM-mediated mechanism.

bioRxiv · Feb 5, 2021Biochemistry