Role of ugt genes in detoxification and glycosylation of 1-hydroxy phenazine (1-HP) in Caenorhabditis elegans
M. Z. Asif, K. A. Nocilla, L. T. Ngo, M. K. Shah, Y. Smadi, Z. A. Hafeez, M. Parnes, A. Manson, J. Glushka, F. E. Leach, A. S. Edison
This study investigates the role of ugt genes in detoxifying 1-hydroxyphenazine (1-HP) in C. elegans, showing that ugt-23 and ugt-49 mutants are more sensitive to 1-HP and produce fewer derivatives.
bioRxiv · Nov 21, 2023 · PreprintBiochemistry