Author

K. A. Spoth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

C. Dubbeldam· 1 shared D. A. Muller· 1 shared D. Serwas· 1 shared H. Siems· 1 shared J. C. Fromme· 1 shared J. R. Feathers· 1 shared K. X. Nguyen· 1 shared L. F. Kourkoutis· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

C. Dubbeldam

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2 papers

Recent·Most cited

Dose-Efficient Cryo-Electron Microscopy for Thick Samples using Tilt-Corrected Scanning Transmission Electron Microscopy, Demonstrated on Cells and Single Particles

Y. Yu, K. A. Spoth, M. Colletta, K. X. Nguyen, S. E. Zeltmann, X. S. Zhang, M. Paraan, M. Kopylov, C. Dubbeldam, D. Serwas, H. Siems, D. A. Muller, L. F. Kourkoutis

This paper introduces tilt-corrected bright-field scanning-TEM (tcBF-STEM) for cryo-EM, showing improved contrast and efficiency for thick samples, with a subnanometer resolution SPA map of a virus-like particle.

bioRxiv · Apr 22, 2024 · PreprintCell Biology

Surpassing the physical Nyquist limit to produce super-resolution cryo-EM reconstructions

J. R. Feathers, K. A. Spoth, J. C. Fromme

This paper demonstrates super-resolution cryo-EM reconstructions that surpass the physical Nyquist limit using a K3 direct electron detector and shows the benefits of lower magnifications for increased particle numbers.

bioRxiv · Nov 9, 2020Biophysics