Molecular determinants for α-tubulin methylation by SETD2
S. Kearns, F. M. Mason, W. K. Rathmell, I. Y. Park, C. Walker, K. A. Verhey, M. A. Cianfrocco
This study identifies the molecular mechanisms by which SETD2 methylates α-tubulin, revealing distinct substrate recognition and catalytic requirements for tubulin versus histone methylation.
bioRxiv · Oct 21, 2020Biochemistry