Author

K. Aktories

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:protein sequence· 1

Frequent Co-Authors

A. Frisbee· 1 shared C. Schwan· 1 shared G. Schmidt· 1 shared J. K. Ebner· 1 shared M. Plessner· 1 shared M. Simpson· 1 shared P. Kumar· 1 shared P. Ng'ang'a· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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1 shared paperImmunology

A. Frisbee

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2 papers

Recent·Most cited

Clostridium difficile binary toxin (CDT) is recognized by the TLR2/6 heterodimer to induce an NF-κB response

M. Simpson, A. Frisbee, P. Kumar, C. Schwan, K. Aktories, W. Petri

The paper shows that CDT is recognized by the TLR2/6 heterodimer, leading to NF-κB and MAPK pathway activation in mice during CDI.

bioRxiv · Sep 8, 2020 · PreprintImmunology

Photorhabdus Luminescens Toxin complex (TCC) a recombinant injection nano-machine - delivery of recombinant Yersinia enterocolitica YopT

G. Schmidt, K. Aktories, P. Ng'ang'a, J. K. Ebner, M. Plessner

The paper describes engineering a toxin complex to deliver recombinant proteins into mammalian cells and demonstrates its efficiency for cargo delivery and quantification.

bioRxiv · Jul 12, 2019 · PreprintBioengineering