Ipomoeassin-F inhibits the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor
S. O'Keefe, P. Roboti, K. B. Duah, G. Zong, H. Schneider, W. Q. Shi, S. High
This study shows that ipomoeassin F inhibits the ER membrane translocation of SARS-CoV-2 spike, ORF8, and ACE2 proteins in vitro.
bioRxiv · Nov 24, 2020Biochemistry