Methemoglobin aggregation is modulated by the anti-sickling drug voxelotor
B. Cove, A. Munoz, A. Singh, G. Jann, K. Brandon, L. Xing, M. J. Cocco
This study investigates how voxelotor affects methemoglobin aggregation at different pH levels, finding it enhances fiber formation at pH 5.5 but reduces aggregation at physiological pH 7.1.
bioRxiv · Jun 16, 2024 · PreprintBiophysics