Navigating cross-reactivity and host species effects in a serological assay: A case study of the microscopic agglutination test for Leptospira serology
R. O. Mummah, A. C. R. Gomez, A. H. Guglielmino, B. Borremans, R. L. Galloway, K. C. Prager, J. O. Lloyd-Smith
This paper examines cross-reactivity and host species effects in serological data using MAT for Leptospira, showing that antibody titers vary by host and lab, and that high titers do not reliably indicate the infecting serovar.
bioRxiv · Mar 5, 2024 · PreprintEcology