(p)ppGpp directly regulates translation initiation during entry into quiescence
S. Diez, J. Ryu, K. Caban, R. L. Gonzalez, J. Dworkin
This study shows that (p)ppGpp inhibits protein synthesis in Bacillus subtilis during quiescence by targeting the GTPase IF2, preventing its allosteric activation during translation initiation.
bioRxiv · Oct 17, 2019Microbiology