Author

K. Chkhaidze

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Sottoriva· 2 shared D. Nichol· 2 shared G. D. Cresswell· 2 shared I. Spiteri· 2 shared J. Fernandez-Mateos· 2 shared T. A. Graham· 2 shared A. Berner· 1 shared A.-M. Baker· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

A. Sottoriva

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2 papers

Recent·Most cited

The co-evolution of the genome and epigenome in colorectal cancer

T. Heide, J. Househam, I. Spiteri, C. Lynn, G. D. Cresswell, M. Mossner, C. Kimberley, J. Fernandez-Mateos, B. Chen, L. Zapata, C. James, I. Barozzi, K. Chkhaidze, D. Nichol, A. Berner, , A. Sottoriva

This study examines the co-evolution of genome and epigenome in colorectal cancer using single-clone spatial multi-omic profiling, revealing epigenetic changes and their impact on mutation accumulation.

Nature · Oct 26, 2022Peer-reviewedCancer Biology

Measuring single cell divisions in human cancers from multi-region sequencing data

B. Werner, J. Case, M. J. Williams, K. Chkhaidze, D. Temko, J. Fernandez-Mateos, G. D. Cresswell, D. Nichol, W. Cross, I. Spiteri, W. Huang, I. Tomlinson, C. P. Barnes, T. A. Graham, A. Sottoriva

This study measures single-cell division rates and survival in human cancers using multi-region sequencing data, revealing per-cell mutation and survival rates across different cancer types and healthy tissues.

bioRxiv · Feb 25, 2019 · PreprintCancer Biology