ImmunoPET-informed sequence for focused ultrasound-targeted mCD47 blockade controls glioma
N. D. Sheybani, S. Paul, K. S. McCauley, V. Breza, S. S. Berr, G. W. Miller, K. D. Neumann, R. J. Price
This study shows that timing mCD47 antibody injection relative to focused ultrasound (FUS) BBB disruption affects antibody delivery to gliomas, with post-FUS injection improving delivery and reducing tumor growth.
bioRxiv · Jul 27, 2020Bioengineering