SALL3 mediates the loss of neuroectodermal differentiation potential in human embryonic stem cells with chromosome 18q loss
C. Spits, Y. Lei, D. Al Delbany, N. Krivec, M. Regin, E. Couvreu de Deckersberg, C. Janssens, M. Ghosh, K. D. Sermon
This study shows that loss of chromosome 18q in human embryonic stem cells impairs neuroectoderm commitment and cardiac progenitor differentiation through SALL3 downregulation.
bioRxiv · Jun 26, 2023 · PreprintCell Biology