Author

E. Couvreu De Deckersberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 5

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Organism:human· 5 Assay:bulk RNA-seq· 4 Research Focus:differential expression· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 2 Approach:statistical model· 2

Frequent Co-Authors

C. Spits· 5 shared A. Keller· 3 shared C. Markouli· 3 shared D. Dziedzicka· 3 shared K. Sermon· 3 shared M. Geens· 3 shared M. Regin· 3 shared N. Krivec· 3 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersCell Biology

C. Spits

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Gain of 1q confers an MDM4-driven growth advantage to undifferentiated and differentiating hESC while altering their differentiation capacity

N. Krivec, E. Couvreu de Deckersberg, Y. Lei, D. Al Delbany, M. Regin, S. Verhulst, L. A. van Grunsven, K. Sermon, C. Spits

This study shows that 1q gain in hESCs increases MDM4 expression, giving a growth advantage during differentiation by reducing DNA damage sensitivity and altering differentiation capacity.

bioRxiv · Sep 19, 2023Cell Biology

SALL3 mediates the loss of neuroectodermal differentiation potential in human embryonic stem cells with chromosome 18q loss

C. Spits, Y. Lei, D. Al Delbany, N. Krivec, M. Regin, E. Couvreu de Deckersberg, C. Janssens, M. Ghosh, K. D. Sermon

This study shows that loss of chromosome 18q in human embryonic stem cells impairs neuroectoderm commitment and cardiac progenitor differentiation through SALL3 downregulation.

bioRxiv · Jun 26, 2023 · PreprintCell Biology

Gains of 12p13.31 delay WNT-mediated initiation of hPSC differentiation and promote residual pluripotency in a cell cycle dependent manner

A. Keller, Y. Lei, N. Krivec, E. Couvreu De Deckersberg, D. Dziedzicka, C. Markouli, K. D. Sermon, M. Geens, C. Spits

This study shows that gains of 12p13.31 in hPSC delay WNT signaling and promote residual pluripotency through NANOG and GDF3, dependent on cell cycle position during differentiation.

bioRxiv · May 22, 2021 · PreprintCell Biology

Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm

D. Dziedzicka, M. Tewary, A. Keller, L. Tilleman, L. Prochazka, J. Östblom, E. Couvreu De Deckersberg, C. Markouli, S. Franck, F. Van Nieuwerburgh, C. Spits, P. W. Zandstra, K. Sermon, M. Geens

The paper shows that endogenous suppression of WNT signaling in hPSCs reduces differentiation efficiency towards definitive endoderm, and that increasing WNT or inhibiting PI3K/AKT can overcome this block.

bioRxiv · Jul 3, 2020Cell Biology

Constitutional activation of BMP4 and WNT signalling in hESC results in impaired mesendoderm differentiation

C. Markouli, E. Couvreu De Deckersberg, D. Dziedzicka, M. Regin, S. Franck, A. Keller, A. Gheldof, M. Geens, K. Sermon, C. Spits

The paper identifies a human embryonic stem cell subline with hyperactivated WNT and BMP4 signaling that impairs mesendoderm differentiation, leading to trophoblast-like cell formation.

bioRxiv · Jun 4, 2020 · PreprintCell Biology