Discovery of the gut microbial enzyme responsible for bilirubin reduction to urobilinogen
B. Hall, S. Levy, K. Default-Tompson, G. Minabou, A. Weiss, D. Braccia, C. Jenkins, Y. Yang, G. Arp, S. Abeysinghe, M. Jermain, D. Wu, X. Jiang
This study identifies BilR, a gut microbial enzyme that reduces bilirubin to urobilinogen, and shows its prevalence in healthy adults and decline in neonates and IBD patients.
bioRxiv · Feb 7, 2023 · PreprintMicrobiology