Author

K. E. Carlson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Approach:deep learning· 1 Approach:statistical model· 1

Frequent Co-Authors

A. J. Paul· 1 shared C. B. Reilly· 1 shared C. E. Fowler· 1 shared C. G. Mayne· 1 shared D. D. Ingber· 1 shared D. J. Hosfield· 1 shared E. Tajkhorshid· 1 shared G. Buchwalter· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

A. J. Paul

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Author profile →

2 papers

Recent·Most cited

Broad-Spectrum Coronavirus Inhibitors Discovered by Modeling Viral Fusion Dynamics

C. B. Reilly, J. Moore, S. Lightbown, A. J. Paul, S. G. Bernier, K. E. Carlson, D. D. Ingber

The paper identifies broad-spectrum coronavirus inhibitors using molecular dynamics and AI docking, showing efficacy against SARS-CoV-2 and related viruses in cell and mouse models.

bioRxiv · Mar 28, 2024Microbiology

The SERM/SERD Bazedoxifene Disrupts ESR1 Helix 12 to Overcome Acquired Hormone Resistance in Breast Cancer Cells

S. W. Fanning, R. Jeselsohn, V. Dharmarajan, C. G. Mayne, M. Karimi, G. Buchwalter, R. Houtman, W. Toy, C. E. Fowler, M. Laine, K. E. Carlson, T. A. Martin, J. Nowak, J. C. Nwachukwu, D. J. Hosfield, , G. L. Greene

This study shows that bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells by inhibiting Y537S and D538G ER mutants more effectively than tamoxifen.

bioRxiv · Apr 23, 2018Cancer Biology