Author

K. E. Cavanaugh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

M. F. Staddon· 2 shared M. L. Gardel· 2 shared S. Banerjee· 2 shared E. M. Munro· 1 shared E. Munro· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 9 mutual co-author links

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2 shared papersBiophysics

M. F. Staddon

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2 papers

Recent·Most cited

Mechanosensitive junction remodelling promotes robust epithelial morphogenesis

M. F. Staddon, K. E. Cavanaugh, E. M. Munro, M. L. Gardel, S. Banerjee

This study shows that mechanosensitive tension remodelling of epithelial junctions enables robust shape changes through a ratcheting mechanism, using optogenetic control and a modified vertex model.

bioRxiv · May 24, 2019Biophysics

RhoA mediates epithelial cell shape changes via mechanosensitive endocytosis

K. E. Cavanaugh, M. F. Staddon, E. Munro, S. Banerjee, M. L. Gardel

This study shows RhoA controls epithelial cell shape through mechanosensitive endocytosis, requiring formin and dynamin, and develops a vertex model to explain junction remodeling.

bioRxiv · Apr 10, 2019Cell Biology