Author

K. El Hage

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Bouhss· 1 shared B. Desforges· 1 shared C. Bauvais· 1 shared D. Pastre· 1 shared E. Steiner· 1 shared F. Bregier· 1 shared H. Henri· 1 shared J. C. Rengifo-Gonzalez· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

A. Bouhss

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Author profile →

2 papers

Recent·Most cited

Enforcing local DNA kinks by sequence-selective trisintercalating oligopeptides of a tricationic porphyrin. A polarizable Molecular Dynamics study.

N. Gresh, K. El Hage, L. Lagardere, F. Bregier, J. Godard, J.-P. Piquemal, M. Perree-Fauvet, V. Sol

This paper uses molecular dynamics to show that BABAP derivatives induce sequence-selective DNA kinks, mimicking DNA-bound Cre recombinase structures.

bioRxiv · Jul 26, 2023Biophysics

Targeting RNA:Protein Interactions with an Integrative Approach Leads tothe Identification of Potent YB-1 Inhibitors

K. El Hage, N. Babault, O. Maciejak, B. Desforges, P. Craveur, E. Steiner, J. C. Rengifo-Gonzalez, H. Henri, M.-J. Clement, V. Joshi, A. Bouhss, L. Wang, C. Bauvais, D. Pastre

The paper identifies potent YB-1 inhibitors using an integrative approach combining microtubule bench assay, NMR, and MD simulations.

bioRxiv · Apr 8, 2022Biophysics