Systematic benchmarking of imaging spatial transcriptomics platforms in FFPE tissues
H. Wang, R. Huang, J. Nelson, C. Gao, M. Tran, A. Yeaton, K. Felt, K. L. Pfaff, T. Bowman, S. J. Rodig, K. Wei, B. A. Goods, S. L. Farhi
This study benchmarks three imaging spatial transcriptomics platforms on FFPE tissues, finding 10x Xenium has higher transcript counts without sacrificing specificity, while all platforms align with RNA-seq data but vary in performance metrics.
bioRxiv · Dec 7, 2023Cancer Biology